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Fig. 6 | Big Data Analytics

Fig. 6

From: Identification of disease-distinct complex biomarker patterns by means of unsupervised machine-learning using an interactive R toolbox (Umatrix)

Fig. 6

3D-display of the U-matrix representation of the lipid marker (Fig. 1) plasma concentration pattern. It shows the Parkinson patients (green dots) are completely separated, i.e., located in a different cluster, from the healthy subjects (blue dots). A clear separation is indicated by a mountain range in the middle of the U*-matrix. The figure has been created using the R software package (version 3.4.0 for Linux; [24]). Specifically, the figures displaying geographical map analogies have been created using the R package “Umatrix” (

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